ABSTRACT
OBJECTIVE:To observe the antiaging effect of celery seed oil (CSO) on aging mice and rats induced by D-galactose. METHODS: Aging models were established with D-galactose hypo. At the same time, the model animals were intragastrically given CSO. After 6 weeks, the effects of CSO on learning and memory were evaluated by step down test and electrophysiological test. And the MDA content, MAO-B and SOD activity in brains of aging mice were measured. RESULTS: CSO can markedly improve the learning and memory of aging mice and rats, reduce the content of MDA and activity of MAO-B, and increase SOD activity. CONCLUSION: CSO has good antiaging effect.
ABSTRACT
Objective:To probe into clinical therapeutic effects of separated TCM compound recipe Xuefu Zhuyu Decoction for combination of disease and syndrome,so as to further expound the law of TCM recipe formulation.Methods:By using randomized double blind placebo control method,123 cases were randomly divided into Xuefu Zhuyu group,refine Xuefu Zhuyu group,drug-pair group and placebo group.Each ease was administered 10ml each time,thrice daily,4 weeks as one course.Results:The therapeutic effect for angina pectoris of coronary heart disease was in order of Xuefu Zhuyu group,refine Xuefu Zhuyu group,drug-pair group and placebo group(P